The Zhao Bioinformatics Laboratory
PlantGRN: Modeling and Deciphering Plant Transcriptional Regulatory Networks   
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Genome-scale Gene Association Network Reconstruction and Analysis for Very Large-scale Expression Data

GPLEXUS implements an innovative function to identify experiment-specific conditions that majorly contribute to gene-gene associations in the constructed networks. Such analysis may greatly aid scientists to understand the regulatory mechanisms behind these interactions. This function is particularly important for studying plants, whose sessile life-style requires them to deal with ambient conditions. Learning subnetworks and their operating conditions will provide opportunities to understand and enhance plant adaptation for increasingly challenging environment conditions.

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   Funding by the National Science Foundation    Funding by the Oklahoma Center for the Advancement of Science & Technology    Additional funding by the Samuel Roberts Noble Foundation


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