To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of ZF-HD family

  ZF-HD
Family Type Transcription factor
Plant Specific No
Functional Domains DNA binding domain
Must-have InterProScan Domain Pattern IPR006456 or IPR006455
Prohibited InterProScan Domain Pattern IPR007087
Description

Homeobox genes encode a typical DNA-binding domain of 60 amino acids, known as homeodomain. Typically, homeodomain folds into characteristic 3D structure containing three alpha-helices, of which the second and third form a helix-turn-helix motif. ZF-HD group of Zn finger proteins have two highly conserved zinc finger?Clike motifs upstream of the homeodomain. The first putative zinc finger has a consensus sequence C-X3-H-X9-D-X1-C, where H is not always conserved, and the second putative zinc finger has the following pattern C-X2-C-X1-C-H-X3-H.

Reference:

1. K. Mukherjee, L. Brocchieri, T. R. Burglin, A comprehensive classification and evolutionary analysis of plant homeobox genes. Mol Biol Evol 26, 2775 (2009).

Cross-reference to other databases

The family is the same family of ZF-HD in PlantTFDB.

The family is the same family of zf-HD in PlnTFDB.



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