To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of SWIB-Plus-3 family

  SWIB-Plus-3
Family Type Chromatin remodeling
Plant Specific Yes
Functional Domains Single Strand DNA binding
Must-have InterProScan Domain Pattern IPR003121 and IPR004343
Prohibited InterProScan Domain Pattern -
Description

SWIB-Plus-3: SWIB (SWI/SNF complex B) domain present ubiquitously in many organism. In Plant and Chlamydia they are present as individual protein (Not embedded in a polypeptide). SWIB domain by itself has been implicated in chromatin remodeling. Plus3 domain by itself has limited number of highly conserved amino acids, among which three positively charged residues are present. Presence of these three residues gave the Plus3 domain its name. Plus3 domain by itself can bind to DNA substrates that are at least partially single-stranded with significant affinity. SWIB-Plus-3 is a unique class of protein the direct role of it is plant development have yet to be implicated.

Reference:

1. R. Bennett-Lovsey, S. E. Hart, H. Shirai, K. Mizuguchi, The SWIB and the MDM2 domains are homologous and share a common fold. Bioinformatics 18, 626 (2002).

2. R. N. de Jong, V. Truffault, T. Diercks, E. Ab, M. A. Daniels, R. Kaptein, G. E. Folkers, Structure and DNA binding of the human Rtf1 Plus3 domain. Structure 16, 149 (2008) 2. J. Melonek, A. Matros, M. Trosch, H. P. Mock, K. Krupinska, The core of chloroplast nucleoids contains architectural SWIB domain proteins. Plant Cell 24, 3060 (2012).

Cross-reference to other databases

The family is only defined in PlantTFcat.



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