To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of SWI-SNF family

  SWI-SNF
Family Type Chromatin remodeling
Plant Specific No
Functional Domains Chromatin-remodelling complex, RSC
Must-have InterProScan Domain Pattern IPR013933
Prohibited InterProScan Domain Pattern -
Description

The Swi/Snf family of nucleosome-remodeling complexes has been shown to play important roles in gene
expression throughout eukaryotes. Genetic and biochemical studies previously suggested that Swi/Snf activates
transcription by remodeling nucleosomes, thereby permitting increased access of transcription factors for their
binding sites. Recent studies have identified additional Swi/Snf biochemical activities and have suggested
possible mechanisms by which Swi/Snf is targeted to specific promoters. Surprisingly, studies have also
revealed that, besides being necessary for activation, Swi/Snf is required for transcriptional repression of some
genes. These analyses have transformed our understanding of the function of the Swi/Snf family of complexes
and suggest that they control transcription in diverse ways.

Reference:

1. P. Sudarsanam, F. Winston, The Swi/Snf family nucleosome-remodeling complexes and transcriptional control. Trends Genet 16, 345 (2000).

Cross-reference to other databases

The family is only defined in PlantTFcat.



  © 2011-2013 by The Samuel Roberts Noble Foundation, Inc.; Designed for 1024x768 resolution