To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of SET family

  SET
Family Type Chromatin remodeling
Plant Specific No
Functional Domains Lysine methyltransferases (KMTs)
Must-have InterProScan Domain Pattern IPR001214 or IPR009207 or IPR017111 or IPR016858 or IPR016569
Prohibited InterProScan Domain Pattern IPR000313 IPR011011 IPR019787 IPR019786 IPR001965 IPR007087 IPR006570
Description

H3K4 trimethylation is frequently associated with the promoters of actively transcribed genes. This modification can function to recruit chromatin remodeling and modifying complexes as well as the basal transcription machinery. SET domain lysine methyltransferases (KMTs) catalyze the site- and state-specific methylation of lysine residues in histone and non-histone substrates. The substrate and product specificities of SET domain KMTs are pivotal to eliciting these effects due to the distinct functions associated with site and state-specific protein lysine methylation.

Reference:

1. T. O. Yeates, Structures of SET domain proteins: protein lysine methyltransferases make their mark. Cell 111, 5 (2002).

Cross-reference to other databases

The family is the same family of SET in PlnTFDB.



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