To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of MYB/SANT family

  MYB/SANT
Family Type Transcription factor
Plant Specific No
Functional Domains DNA binding and histone modification
Must-have InterProScan Domain Pattern IPR017884
Prohibited InterProScan Domain Pattern -
Description

SANT domains (for ??switching-defective protein 3 (Swi3), adaptor 2 (Ada2), nuclear receptor co-repressor (N-CoR), transcription factor (TF)IIIB??). The SANT domain was initially identified as an approximately 50-amino-acid motif that is present in nuclear receptor co-repressors. Further sequence analysis highlighted a strong similarity to the DNA-binding domain (DBD) of Myb-related proteins. Initial sequence alignments, as well as secondary structure predictions, indicated that the SANT domain also consists of three ??-helices, each of which contains a corresponding, bulky aromatic residue. An essential role for the SANT domain in histone acetylation.

Reference:

1. L. A. Boyer, R. R. Latek, C. L. Peterson, The SANT domain: a unique histone-tail-binding module? Nat Rev Mol Cell Biol 5, 158 (2004).

Cross-reference to other databases

The family is the subfamily family of MYB in PlantTFDB.

The family is the subfamily family of MYB in PlnTFDB.



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