The MYB (myeloblastosis) transcription factor family is present in all eukaryotes. MYB DNA-binding domain, contains ~52 amino acid residues in length and forms a helix-turn-helix fold with three regularly spaced tryptophan residues. Based on the number of adjacent MYB repeats, MYB transcription factors are classified into four major groups, namely 1R-MYB, 2R-MYB, 3R-MYB and 4R-MYB containing one, two, three and four MYB repeats, respectively. In animals, R1R2R3- type MYB domain proteins are predominant, while in plants, the R2R3-type
MYB-related genes are those transcription factors they have only one MYB domain. MYB domain proteins are more prevalent.
1. C. Martin, J. Paz-Ares, MYB transcription factors in plants. Trends Genet 13, 67 (1997) 2. A. Katiyar, S. Smita, S. K. Lenka, R. Rajwanshi, V. Chinnusamy, K. C. Bansal, Genome-wide classification and expression analysis of MYB transcription factor families in rice and Arabidopsis. BMC Genomics 13, 544 (2012).