To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of LIM family

  LIM
Family Type Transcription factor interactor and regulator
Plant Specific No
Functional Domains DNA binding domain
Must-have InterProScan Domain Pattern IPR001781
Prohibited InterProScan Domain Pattern IPR001245 IPR001356 IPR009057
Description

Cys2His2 (C2H2)-type zinc fingers are widespread DNA binding motifs in eukaryotic transcription factors. Two cysteine and two histidine residues located in certain positions bind zinc to stabilize the structure. The number of zinc fingers in a single protein can vary over a wide range, and single zinc finger containing transcription factors are only present in plant kingdom. LIM domains coordinate one or more zinc atoms, and are named after the three proteins (LIN-11, Isl1 and MEC-3) in which they were first found. They consist of two zinc-binding motifs that resemble GATA-like Znf's, however the residues holding the zinc atom(s) are variable, involving Cys, His, Asp or Glu residues.

Reference:

1. J. W. Michelsen, K. L. Schmeichel, M. C. Beckerle, D. R. Winge, The LIM motif defines a specific zinc-binding protein domain. Proc Natl Acad Sci U S A 90, 4404 (1993).

Cross-reference to other databases

The family is the same family of LIM in PlnTFDB.



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