To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of Hap2/NF-YA family

  Hap2/NF-YA
Family Type Transcription factor
Plant Specific No
Functional Domains DNA binding domain/Protein-Protein interacting domain
Must-have InterProScan Domain Pattern IPR001289 or IPR018362
Prohibited InterProScan Domain Pattern -
Description

In most species, Nuclear Factor Y (NF-Y) transcription factors are present. They usually composed three subunits: NF-YA/HAP2, NF-YB/HAP3, and NF-YC/HAP5. This group of TF has been implicated in diverse developmental process from animal to plant.
Plant genes belonging to the NF-YA family encode putative TFs. NF-YA??s DNA binding domain, shares some homology with the CCT domain of the nuclear flowering time regulator CONSTANS (CO). NF-YA proteins are characterized by two domains one is a (A1) of 20 amino acids forming a putative alpha helix that appears to be crucial for the interaction with NF-YB and NF-YC. A second adjacent domain (A2) of 21 amino acids, separated from A1 by a conserved linker sequence, was shown to be required for specific DNA binding to CCAAT boxes.

Reference:

1. T. Laloum, S. De Mita, P. Gamas, M. Baudin, A. Niebel, CCAAT-box binding transcription factors in plants: Y so many? Trends Plant Sci, (2012).

Cross-reference to other databases

The family is the synonymous family of NF-YA in PlantTFDB.

The family is the subfamily family of CCAAT in PlnTFDB.



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