To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of GRAS family

  GRAS
Family Type Transcription factor
Plant Specific Yes
Functional Domains DNA binding domain/Protein-Protein interacting domain
Must-have InterProScan Domain Pattern IPR005202 or IPR021914
Prohibited InterProScan Domain Pattern -
Description

GRAS is plant-specific transcription factor family. The protein is named after the first three members: GIBBERELLIC-ACID INSENSITIVE (GAI), REPRESSOR of GAI (RGA) and SCARECROW (SCR). This group of TFs have a charged region between which has similarity to the basic domain of the basic?Cleucine zipper family of TFs. A second leucine heptad repeat is found toward the carboxyl terminus. . Since leucine heptad repeats have been demonstrated to mediate protein?Cprotein interactions, it is predicted that GRAS family of TF have both direct DNA binding and protein-protein interacting domain.

Reference:

1. L. Di Laurenzio, J. Wysocka-Diller, J. E. Malamy, L. Pysh, Y. Helariutta, G. Freshour, M. G. Hahn, K. A. Feldmann, P. N. Benfey, The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. Cell 86, 423 (1996).

2. S. Hirsch, G. E. Oldroyd, GRAS-domain transcription factors that regulate plant development. Plant Signal Behav 4, 698 (2009).

Cross-reference to other databases

The family is the same family of GRAS in PlantTFDB.

The family is the same family of GRAS in PlnTFDB.



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