To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
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Location:  Details of C3H family

  C3H
Family Type Transcription factor
Plant Specific No
Functional Domains RNA binding/ DNA binding domain
Must-have InterProScan Domain Pattern IPR000571
Prohibited InterProScan Domain Pattern IPR001965 IPR000330 IPR007087 IPR000306 IPR001005
Description

CCCH zinc finger proteins are characterized by three cysteine residues and one histidine residue that coordinate the zinc ion and form, a CCCH-type zinc finger. In plant the most abundant type of CCCH finger is C-X8-C-X5-C-X3-H followed by C-X7-C-X5-C-X3-H other rare type of Zn-finger are also available in plant such as C-X7-C-X4-C-X3-H, C-X5-C-X4-C-X3-H, C-X7-CX6-C-X3-H etc. Although the majority of the CCCH motifs bind RNA, DNA binding CCCH-type zinc finger proteins have also been confirmed. Arabidopsis PEI encodes a protein containing a C3H zinc finger domain.

Reference:

1. X. Peng, Y. Zhao, J. Cao, W. Zhang, H. Jiang, X. Li, Q. Ma, S. Zhu, B. Cheng, CCCH-type zinc finger family in maize: genome-wide identification, classification and expression profiling under abscisic acid and drought treatments. PLoS One 7, e40120 (2012).

2. Z. Li, T. L. Thomas, PEI1, an embryo-specific zinc finger protein gene required for heart-stage embryo formation in Arabidopsis. Plant Cell 10, 383 (1998).

Cross-reference to other databases

The family is the same family of C3H in PlantTFDB.

The family is the same family of C3H in PlnTFDB.



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