To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of C2H2 family

  C2H2
Family Type Transcription factor
Plant Specific No
Functional Domains DNA/RNA binding domain and/Protein-Protein interacting domain
Must-have InterProScan Domain Pattern IPR007087 or IPR015880 or IPR013087 or IPR001841
Prohibited InterProScan Domain Pattern IPR003349 IPR001965 IPR003349 IPR001965 IPR011011 IPR000306 IPR003888 IPR003889 IPR001356
Description

Cys2His2 (C2H2)-type zinc fingers are widespread DNA binding motifs in eukaryotic transcription factors. Two cysteine and two histidine residues located in certain positions bind zinc to stabilize the structure. The number of zinc fingers in a single protein can vary over a wide range, and single zinc finger containing transcription factors are only present in plant kingdom. Besides DNA binding, zinc fingers can also provide protein-protein and RNA-protein interactions.

Reference:

1. S. V. Razin, V. V. Borunova, O. G. Maksimenko, O. L. Kantidze, Cys2His2 zinc finger protein family: classification, functions, and major members. Biochemistry (Mosc) 77, 217 (2012)

Cross-reference to other databases

The family is the same family of C2H2 in PlantTFDB.

The family is the same family of C2H2 in PlnTFDB.



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