To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of Bromodomain family

  Bromodomain
Family Type Chromatin remodeler
Plant Specific No
Functional Domains Histone acetylation binding domain
Must-have InterProScan Domain Pattern IPR001487 or IPR018359
Prohibited InterProScan Domain Pattern IPR013178 IPR003888 IPR003889 IPR001005 IPR015495
Description

Proteins containing bromodomains are small helical interaction modules, capable of binding to acetylated histone tails and have a role in recognizing acetylated chromatin. Histone tails acetylation is commonly an indicative mark of open chromatin architecture and transcriptional activation. Bromodomain is present in diverse eukaryotic species. They have a conserved 120 residue structural four helix motif. In Arabidopsis mutantion of bromodomain linked it with seed germinationas as well as for establishment of leaf shape.

Reference:

1. P. Filippakopoulos, S. Knapp, The bromodomain interaction module. FEBS Lett 586, 2692 (2012) 2. C. A. Airoldi, F. D. Rovere, G. Falasca, G. Marino, M. Kooiker, M. M. Altamura, S. Citterio, M. M. Kater, The Arabidopsis BET bromodomain factor GTE4 is involved in maintenance of the mitotic cell cycle during plant development. Plant Physiol 152, 1320 (2010)

Cross-reference to other databases

The family is only defined in PlantTFcat.



  © 2011-2013 by The Samuel Roberts Noble Foundation, Inc.; Designed for 1024x768 resolution