To support the continuous development of PlantTFcat, please cite: Xinbin Dai, Senjuti Sinharoy, Michael K. Udvardi and Patrick X. Zhao, PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool, BMC Bioinformatics, 2013, 14:321, doi:10.1186/1471-2105-14-321.
The Zhao Bioinformatics Laboratory
PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool   
  About Analysis Family Help
Location:  Details of ARB1 family

  ARB1
Family Type Post-transcriptional gene silencing
Plant Specific No
Functional Domains Protein-protein interacting Domain
Must-have InterProScan Domain Pattern IPR018606
Prohibited InterProScan Domain Pattern -
Description

In the RISC, the RNA-induced silencing complex along with DICER, two proteins, Arb1 and Arb2, both of which are required for histone H3 Lys9 (H3-K9) methylation, heterochromatin assembly and siRNA generation. Arb1 and Arb2 inhibit the release of the siRNA passenger strand from Ago1.

Reference:

1. Buker, S.M., Iida, T., Buhler, M., Villen, J., Gygi, S.P., Nakayama, J., and Moazed, D. (2007). Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast. Nat Struct Mol Biol 14, 200-207.

2. Kamminga, L.M., and Ketting, R.F. (2011). RNAi genes pave their own way. Genes Dev 25, 529-533.

Cross-reference to other databases

The family is only defined in PlantTFcat.



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